Q-Tube Assisted Green Synthesis of Bis(Azoles) and Bis(Azines) Linked to Arene Unit

We reported herein efficient green procedures for the synthesis of arene-linked bis(azoles) and bis(azines) using bis(enaminone) as a key intermediate. For this purpose, were reacted with different nucleophiles under pressurized reaction “Q-tube system” to afford target bis(azines). The structures compounds confirmed via considering their elemental analyses well spectral data. used protocol shows beneficial effect on time yields compared conventional conditions.